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Team Hänel


Viral Proteins

The topics of the group are structural and functional aspects of viral proteins with the main focus on accessory and regulatory proteins of viruses. For this purpose we examine their 3D structures and their interactions with host cellular proteins or other virus proteins. The respective protein-protein-interactions are characterized with biophysical, biochemical and cell biological methods.

Research Areas:

Project-Support: Expression and purification of recombinant proteins

Various biophysical methods require large amounts of recombinantly expressed and purified proteins. Additionally, preparation of stable isotope labeled protein is a prerequisite for elucidating their three-dimensional structures by NMR. Therefore, we construct and use efficient recombinant expression systems for the proteins of our interest.

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