Florian Bleffert, Joachim Granzin, Muttalip Caliskan, Stephan N Schott-Verdugo, Meike Siebers, Björn Thiele, Laurence Rahme, Sebastian Felgner, Peter Dörmann, Holger Gohlke* , Renu Batra-Safferling*, Karl-Erich Jaeger, Filip Kovacic* Structural, mechanistic, and physiological insights into phospholipase A-mediated membrane phospholipid degradation in Pseudomonas aeruginosa. eLife 11, e72824 (2022) https://doi.org/10.7554/eLife.72824
Hemmer S, Schulte M, Knieps-Grünhagen E, Granzin J, Willbold D, Jaeger KE, Batra-Safferling R, Panwalkar V, Krauss U. Residue alterations within a conserved hydrophobic pocket influence light, oxygen, voltage photoreceptor dark recovery. Photochem Photobiol Sci , (2022) https://doi.org/10.1007/s43630-022-00346-5
Weiergräber OH, Petrović D, Kislat A, Pattky M, Fabig J, Batra-Safferling R, Schulte am Esch J, Hänel K, Huhn C, Strodel B, Homey B, Willbold D Structure and Dynamics of Human Chemokine CCL16—Implications for Biological Activity Biomolecules 12, 1588 (2022) https://doi.org/10.3390/biom12111588
Arinkin V, Granzin J, Krauss U, Jaeger KE, Willbold D, Batra-Safferling R. Structural determinants underlying the adduct lifetime in the LOV proteins of Pseudomonas putida. FEBS J 288(16), 4955-4972 (2021) https://doi.org/10.1111/febs.15785
Röllen K, Granzin J, Remeeva A, Davari MD, Gensch T, Nazarenko VV, Kovalev K, Bogorodskiy A, Borshchevskiy V, Hemmer S, Schwaneberg U, Gordeliy V, Jaeger KE, Batra-Safferling R, Gushchin I, Krauss U. The molecular basis of spectral tuning in blue- and red-shifted flavin-binding fluorescent proteins. J Biol Chem 296, 100662 (2021) https://doi.org/10.1016/j.jbc.2021.100662
Stadler AM, Granzin J, Cousin A, Batra-Safferling R. Phosphorylated peptide of G protein-coupled receptor induces dimerization in activated arrestin. Scientific Reports 10, 10938 (2020) https://doi.org/10.1038/s41598-020-67944-0
Fettweiss T, Röllen K, Granzin J, Reiners O, Endres S, Drepper T, Willbold D, Jaeger KE, Batra-Safferling R*, Krauss U* Mechanistic Basis of the Fast Dark Recovery of the Short LOV Protein DsLOV from Dinoroseobacter shibae. Biochemistry 57, 4833–4847 (2018) http://dx.doi.org/10.1021/acs.biochem.8b00645
Röllen, K.; Granzin, J.; Batra-Safferling, R*.; Stadler, A.M*. Small-angle X-ray scattering study of the kinetics of light-dark transition in a LOV protein PLoS One 13(7):e0200746, (2018) http://dx.doi.org/10.1371/journal.pone.0200746
Arinkin V, Granzin J, Röllen K, Krauss U, Jaeger KE, Willbold D, Batra-Safferling R. Structure of a LOV protein in apo-state and implications for construction of LOV-based optical tools Scientific Reports 7(42971), (2017) http://dx.doi.org/10.1038/srep42971
Batra-Safferling R and Granzin J. The Structure of the Polar Core Mutant R175E and Its Functional Implications. The Structural Basis Of Arrestin Functions, Vsevolod V. Gurevich (Editor); Springer International Publishing Chapter 11, 143-158 (2017) ISBN: 978-3-319-57552-0
Schlesinger R, Cousin A, Granzin J, Batra-Safferling R. Expression and purification of arrestin in yeast Saccharomyces cerevisiae. Methods Cell Biol 142, 159-172 (2017) https://doi.org/10.1016/bs.mcb.2017.07.003
Röllen K, Granzin J, Panwalkar V, Arinkin V, Rani R, Hartmann R, Krauss U, Jaeger KE, Willbold D, Batra-Safferling R. Signaling States of a Short Blue-Light Photoreceptor Protein PpSB1-LOV Revealed from Crystal Structures and Solution NMR Spectroscopy. J Mol Biol. 428, 3721 - 3736 (2016) http://dx.doi.org/10.1016/j.jmb.2016.05.027 http://www.ncbi.nlm.nih.gov/pubmed/27291287
Endres S, Granzin J, Circolone F, Stadler A, Krauss U, Drepper T, Svensson V, Knieps-Grünhagen E, Wirtz A, Cousin A, Tielen P, Willbold D, Jaeger K-E, Batra-Safferling R Structure and function of a short LOV protein from the marine phototrophic bacterium Dinoroseobacter shibae. BMC Microbiology 15, 30 (2015) http://www.biomedcentral.com/1471-2180/15/30
Circolone F, Granzin J, Jentzsch K, Drepper T, Jaeger K-E, Willbold D, Krauss U, Batra-Safferling R Structural basis for the slow dark recovery of a full-length LOV protein from Pseudomonas putida. J. Mol. Biol. 417, 362–374 (2012)
Granzin J, Cousin A, Weirauch M, Schlesinger R, Büldt G, Batra-Safferling R Crystal structure of p44, a constitutively active splice variant of visual arrestin. J Mol Biol. 416(5), 611-8 (2012) http://dx.doi.org/10.1016/j.jmb.2012.01.028
Batra-Safferling R, Granzin J, Moedder S, Hoffmann S, Willbold D Structural studies of PI3K SH3 domain in complex with a peptide ligand: Role of anchor residue in ligand binding. Biol. Chem. 391, 33-42 (2010)
Funke SA, van Groen T, Kadish I, Bartnik D, Nagel-Steger L, Brener O, Sehl T, Batra-Safferling R, Moriscot C, Schoehn G, Horn AHC, Müller-Schiffmann A, Korth C, Sticht H, Willbold D Oral Treatment with the D-Enantiomeric Peptide D3 Improves Pathology and Behavior of Alzheimer’s disease Transgenic Mice ACS Chem. Neurosci. 1, 639-648 (2010) http://dx.doi.org/10.1021/cn100057j Highlighted in: Chemical & Engineering News, 88(33), August 16, 2010
Batra-Safferling R, Abaraca-Heidemann K, Körschen HG, Tziatzios C, Stoldt M, Budyak I, Willbold D, Schwalbe H, Klein-Seetharaman J, Kaupp UB Glutamic acid-rich proteins of rod photoreceptors are natively unfolded. J Biol Chem 281, 1449-1460 (2006)
