Dobner J, Simons IM, Rufinatscha K, Hänsch S, Schwarten M, Weiergräber OH, Abdollahzadeh I, Gensch T, Bode JG, Hoffmann S, Willbold D. Deficiency of GABARAP but Not Its Paralogs Causes Enhanced EGF-induced EGFR Degradation Cells 9, 1296 (2020) https://doi.org/10.3390/cells9051296 https://www.mdpi.com/2073-4409/9/5/1296
Sanwald JL, Dobner J, Simons IM, Poschmann G, Stühler K, Üffing A, Hoffmann S, Willbold D Lack of GABARAP-Type Proteins Is Accompanied by Altered Golgi Morphology and Surfaceome Composition Int J Mol Sci 22(1), 85 (2020) https://doi.org/10.3390/ijms22010085 https://www.mdpi.com/1422-0067/22/1/85
Abdollahzadeh I, Hendriks J, Sanwald JL, Simons IM, Hoffmann S, Weiergräber OH, Willbold D, Gensch T Autophagy-Related Proteins GABARAP and LC3B Label Structures of Similar Size but Different Shape in Super-Resolution Imaging Molecules 24, E1833 (2019) https://doi.org/10.3390/molecules24091833
Klinker S, Stindt S, Gremer L, Bode JG, Gertzen CGW, Gohlke H, Weiergräber OH, Hoffmann S, Willbold D Phosphorylated tyrosine 93 of hepatitis C virus nonstructural protein 5A is essential for interaction with host c-Src and efficient viral replication J Biol Chem 294, 7388-7402 (2019) https://doi.org/10.1074/jbc.RA119.007656
Simons IM, Mohrlüder J, Feederle R, Kremmer E, Zobel T, Dobner J, Bleffert N, Hoffmann S, Willbold D The highly GABARAP specific rat monoclonal antibody 8H5 visualizes GABARAP in immunofluorescence imaging at endogenous levels Sci Rep 9, 526 (2019) https://doi.org/10.1038/s41598-018-36717-1
Boeske A, Schwarten M, Ma P, Tusche M, Mötter J, Möller C, Neudecker P, Hoffmann S, Willbold D Direct binding to GABARAP family members is essential for HIV-1 Nef plasma membrane localization Scientific Reports 7, 5979 (2017)
Hung Y-F, Schwarten M, Hoffmann S, Willbold D, Sklan EH, Koenig BW Amino Terminal Region of Dengue Virus NS4A Cytosolic Domain Binds to Highly Curved Liposomes Viruses 7, 4119-4130 (2015) Link
Hung Y-F, Schwarten M, Schünke S, Thiagarajan-Rosenkranz P, Hoffmann S, Sklan EH, Willbold D, Koenig BW Dengue virus NS4A cytoplasmic domain binding to liposomes is sensitive to membrane curvature BBA - Biomembranes 1848, 1119-1126 (2015)
Aladag A, Hoffmann S, Stoldt M, Bösing C, Willbold D, Schwarten M Hepatitis C virus NS5A is able to competitively displace c-Myc from the Bin1 SH3 domain in vitro J. Pept. Science 20, 334-340 (2014)
Hung Y-F, Valdau O, Schünke S, Stern O, Koenig BW, Willbold D, Hoffmann S Recombinant production of the amino terminal cytoplasmic region of dengue virus non-structural protein 4A for structural studies PLoS ONE 9, e86482 (2014) Link
Ma P, Schwarten M, Schneider L, Boeske A, Henke N, Lisak D, Weber S, Mohrlüder J, Stoldt M, Strodel B, Methner A, Hoffmann S, Weiergräber OH, Willbold D Interaction of Bcl-2 with the autophagy-related GABAA receptor-associated protein (GABARAP): Biophysical characterization and functional implications J Biol Chem 288, 37204-37215 (2013)
Schwarten M, Solyom Z, Feuerstein S, Aladag A, Hoffmann S, Willbold D, Brutscher B Interaction of non-structural protein 5A of hepatitis C virus with SH3 domains using non-canonical binding sites Biochemistry 52, 6160-6168 (2013)
Stern O, Hung Y-F, Valdau O, Yaffe Y, Harris E, Hoffmann S, Willbold D, Sklan E An N-terminal amphipathic helix in the Dengue virus nonstructural protein 4A mediates oligomerization and is essential for replication. J. Virol. 87, 4080-4085 (2013)
Feuerstein S, Solyom Z, Aladag A, Favier A, Schwarten M, Hoffmann S, Willbold D, Brutscher B Transient structure and SH3 interaction sites in an intrinsically disordered fragment of the hepatitis C virus protein NS5A. J. Mol. Biol. 420, 310-323 (2012)
Kammula E, Moetter J, Gorgels A, Jonas E, Hoffmann S, Willbold D Brain transcriptome-wide screen for HIV-1 Nef protein interaction partners reveals various membrane-associated proteins. PLoS ONE 7, e51578 (2012) http://dx.doi.org/10.1371/journal.pone.0051578 full text open access
Feuerstein S, Solyom Z, Aladag A, Hoffmann S, Willbold D, Brutscher B 1H, 13C, and 15N resonance assignment of a 179 residue fragment of hepatitis C virus nonstructural protein 5A Biomol. NMR Assign. 53, 241-243 (2011)
Batra-Safferling R, Granzin J, Moedder S, Hoffmann S, Willbold D Structural studies of PI3K SH3 domain in complex with a peptide ligand: Role of anchor residue in ligand binding. Biol. Chem. 391, 33-42 (2010)
Glück JM, Hoffmann S, Koenig BW, Willbold D Single Vector System for Efficient N-myristoylation of Recombinant Proteins in E. coli PLoS ONE 5, e10081 (2010) full text open access The plasmids in this publication can be received via https://www.addgene.org/Dieter_Willbold/
Hoffmann S, Funke SA, Wiesehan K, Moedder S, Glück JM, Feuerstein S, Gerdts M, Moetter J, Willbold D Competitively selected protein ligands pay theirs increase in specificity by a decrease in affinity. Mol. BioSyst 6, 116-123 (2010)
Glück JM, Wittlich M, Feuerstein S, Hoffmann S, Willbold D, Koenig BW Integral membrane proteins in nanodiscs can be studied by solution NMR spectroscopy. J. Am. Chem. Soc. 131, 12060-61 (2009)
Hoffmann S, Jonas E, Konig S, Preusser-Kunze A, Willbold D Nef protein of human immunodeficiency virus type 1 binds its own myristoylated N-terminus. Biol. Chem. 366, 181-183 (2007)
Schmidt H, Hoffmann S, Tran T, Stoldt M, Stangler T, Wiesehan K, Willbold D Solution structure of a Hck SH3 domain ligand complex reveals novel interaction modes. J. Mol. Biol. 365, 1517-1532 (2007)
Stangler T, Tran T, Hoffmann S, Schmidt H, Jonas E, Willbold D Competitive displacement of full-length HIV-1 Nef from Hck SH3 domain by a high affinity artificial peptide. Biol. Chem. 388, 611-615 (2007)
Wittlich M, Koenig BW, Hoffmann S, Willbold D Structural characterisation of the transmembrane and cytoplasmic domains of human CD4. Biochim Biophys Acta 1768, 2949-60 (2007)
Bauer F, Schweimer K, Meiselbach H, Hoffmann S, Rösch P, Sticht H Structural characterization of Lyn-SH3 domain in complex with a herpesviral protein reveals an extended recognition motif that enhances binding affinity Protein Sci. 14, 2487-98 (2005)
Hofmann G, Schweimer K, Kiessling A, Hofinger E, Bauer F, Hoffmann S, Rösch P, Campbell ID, Werner JM, Sticht H Binding, domain orientation, and dynamics of the Lck SH3-SH2 domain pair and comparison with other Src-family kinases Biochemistry 44, 13043-50 (2005)
Tran T, Hoffmann S, Wiesehan K, Jonas E, Luge C, Aladag A, Willbold D Insights into human Lck SH3 domain binding specificity: different binding modes of artificial and native ligands. Biochemistry 44, 15042-15052 (2005)
Bauer F, Hofinger E, Hoffmann S, Rösch P, Schweimer K, Sticht H Characterization of Lck-binding elements in the herpesviral regulatory Tip protein Biochemistry 43, 14932-9 (2004)
Lehmann K, Hoffmann S, Neudecker P, Suhr M, Becker WM, Rösch P High-yield expression in Escherichia coli, purification, and characterization of properly folded major peanut allergen Ara h 2 Protein Expr. Purif. 31, 250-9 (2003)
Neudecker P, Lehmann K, Nerkamp J, Haase T, Wangorsch A, Fotisch K, Hoffmann S, Rösch P, Vieths S, Scheurer S Mutational epitope analysis of Pru av 1 and Api g 1, the major allergens of cherry (Prunus avium) and celery (Apium graveolens): correlating IgE reactivity with three-dimensional structure Biochem J. 15, 97-107 (2003)
Schweimer K, Kiessling A, Bauer F, Hor S, Hoffmann S, Rösch P, Sticht H Sequence-specific 1H, 13C and 15N resonance assignments of the SH3-SH2 domain pair from the human tyrosine kinase Lck J. Biomol. NMR 27, 405-406 (2003)
Schweimer K, Hoffmann S, Bauer F, Friedrich U, Kardinal C, Feller SM, Biesinger B, Sticht H Structural investigation of the binding of a herpesviral protein to the SH3 domain of tyrosine kinase Lck Biochemistry 41, 5120-30 (2002)
Briese L, Hoffmann S, Friedrich U, Biesinger B, Willbold D Sequence-specific 1H, 13C and 15N resonance assignments of lymphocyte specific kinase unique and SH3 domains. J. Biomol. NMR 19, 193-194 (2001)
Jonas G, Hoffmann S, Willbold D Binding of phage displayed HIV-1 Tat to TAR RNA in the presence of Cyclin T1. J. Biomed. Sci. 8, 340-346 (2001)
Lauber T, Marx UC , Schulz A, Kreutzmann P, Rösch P,Hoffmann S Accurate Disulfide Formation in E. coli: Overexpression and Characterization of the First Domain (HF6478) of the Multiple Kazal Type Inhibitor LEKTI Prot. Expr. Purif. 22, 108-112 (2001)
Schärpf M, Sticht H, Schweimer K, Boehm M, Hoffmann S, Rösch, P Antitermination in the bacteriophage l: The structure of the N36 peptide-boxB RN A complex Eur. J. Biochem. 267, 2397-2408 (2000)
Schweimer K, Hoffmann S, Wastl J, Maier U-G, Rösch P, Sticht H Solution structure of a zinc substituted rubredoxin from the cryptomonad Guillardia theta Protein Sci. 9, 1474-86 (2000)
Wastl J, Iuzzolino L, Dörner W, Duin E, Link T, Hoffmann S, Sticht H, Dau H, Lingelbach K, Maier U-G Eukaryotically encoded and chloroplast located rubredoxin is associated with photosystem II J. Biol. Chem. 275, 30058-30063 (2000)
Wastl J, Sticht, Maier U-G, Rösch P, Hoffmann S Identification and characterization of a eukaryotically encoded rubredoxin in a cryptomonad alga FEBS Letters 471, 191-196 (2000)
Hoffmann S, Willbold D A selection system to study protein-RNA interactions: Functional display of HIV-1 Tat protein on filamentous bacteriophage M13 Biochem. Biophys. Res. Comm. 235, 806-811 (1997)
Metzger AU, Bayer B, Willbold D, Hoffmann S, Frank RW, Goody RS, Rösch P The interaction of HIV-1 Tat (32-72) with its target RNA: A Fluorescence and Nuclear Magnetic Resonance Study Biochem. Biophys. Res. Comm. 241, 31-36 (1997)
Metzger AU, Bayer P, Willbold D, Hoffmann S, Frank RW, Goody RS, Rösch P The interaction of HIV-1 Tat (32-72) with its target RNA: A Fluorescence and Nuclear Magnetic Resonance Study. Biochem. Biophys. Res. Comm. 241, 31-36 (1997)
Willbold D, Hoffmann S, Rösch P Secondary structure and tertiary fold of the human immunodeficiency virus protein U (Vpu) cytoplasmic domain in solution Eur. J. Biochem. 245, 581-588 (1997)
