Heid LF, Agerschou ED, Orr AA, Kupreichyk T, Schneider W, Wördehoff MM, Schwarten M, Willbold D, Tamamis P, Stoldt M, Hoyer W Sequence-based identification of amyloidogenic β-hairpins reveals a prostatic acid phosphatase fragment promoting semen amyloid formation Comput Struct Biotechnol J 23, 417-430 (2024) https://doi.org/10.1016/j.csbj.2023.12.023
Schulz CM, Agerschou ED, Gardon L, Alexander M, Stoldt M, Heise H, Tamgüney G, Hoyer W Disordered regions of inhibitor-bound α-synuclein suppress seed-induced fibril nucleation in cells Cell Rep Phys Sci , 102180 (2024) https://doi.org/10.1016/j.xcrp.2024.102180
Heid LF, Kupreichyk T, Schützmann MP, Schneider W, Stoldt M, Hoyer W Nucleation of α-Synuclein Amyloid Fibrils Induced by Cross-Interaction with β-Hairpin Peptides Derived from Immunoglobulin Light Chains Int J Mol Sci 24, 16132 (2023) https://doi.org/10.3390/ijms242216132
Braczynski AK, Sevenich M, Gering I, Kupreichyk T, Agerschou ED, Kronimus Y, Habib P, Stoldt M, Willbold D, Schulz JB, Bach JP, Falkenburger BH, Hoyer W Alpha-synuclein-specific naturally occurring antibodies inhibit aggregation in vitro and in vivo Biomolecules 12, 469 (2022) https://doi.org/10.3390/biom12030469
Kukuk L, Dingley AJ, Granzin J, Nagel-Steger L, Thiagarajan-RosenkranzP, Ciupka D, Hänel K, Batra-Safferling R, Pacheco V, Stoldt M, PfefferK, Beer-Hammer S, Willbold D, Koenig BW Structure of the SLy1 SAM homodimer reveals a new interface for SAM domain self-association Scientific Reports 9, 54 (2019) https://doi.org/10.1038/s41598-018-37185-3
Dammers C, Reiss K, Gremer L, Lecher J, Ziehm T, Stoldt M, Schwarten M, Willbold D. Pyroglutamate-modified amyloid-β(3-42) shows α-helical intermediates before amyloid formation. Biophys. J. 112, 1621-1633 (2017)
Panwalkar V, Neudecker P, Schmitz M, Lecher J, Schulte M, Medini K, Stoldt M, Brimble MA, Willbold D, Dingley AJ. The Nedd4-1 WW Domain Recognizes the PY Motif Peptide through Coupled Folding and Binding Equilibria Biochemistry 55, 659-674 (2016) http://pubs.acs.org/doi/full/10.1021/acs.biochem.5b01028
Börger C, Schünke S, Lecher J, Stoldt M, Winkhaus F, Kaupp UB, Willbold D Resonance assignment of the ligand-free cyclic nucleotide-binding domain from the murine ion channel HCN2 Biomol. NMR Assign. 9, 243-246 (2015)
Ma P, Schillinger O, Schwarten M, Lecher J, Hartmann R, Stoldt M, Mohrlüder J, Olubiyi O, Strodel B, Willbold D, Weiergräber OH Conformational Polymorphism in Autophagy-Related Protein GATE-16 Biochemistry 54, 5469-5479 (2015)
Shaykhalishahi H, Gauhar A, Wördehoff MM, Grüning CS, Klein A, Bannach O, Stoldt M, Willbold D, Härd T, Hoyer W Contact between the beta1 and beta2 segments of alpha-synuclein that inhibits amyloid formation Angew. Chem. Int. Ed. 54, 8837-8840 (2015) http://dx.doi.org/10.1002/anie.201503018
Shaykhalishahi H, Mirecka EA, Gauhar A, Grüning CSR, Willbold D, Härd T, Stoldt M, Hoyer W A beta-hairpin-binding protein for three different disease-related amyloidogenic proteins ChemBioChem 16, 411-414 (2015) http://dx.doi.org/10.1002/cbic.201402552
Aladag A, Hoffmann S, Stoldt M, Bösing C, Willbold D, Schwarten M Hepatitis C virus NS5A is able to competitively displace c-Myc from the Bin1 SH3 domain in vitro J. Pept. Science 20, 334-340 (2014)
Grüning CS, Mirecka EA, Klein AN, Mandelkow E, Willbold D, Marino SF, Stoldt M, Hoyer W Alternative conformations of the tau repeat domain in complex with an engineered binding protein J. Biol. Chem. 289, 23209-23218 (2014) http://dx.doi.org/10.1074/jbc.M114.560920
Mirecka EA, Gremer L, Schiefer S, Oesterhelt F, Stoldt M, Willbold D, Hoyer W Engineered aggregation inhibitor fusion for production of highly amyloidogenic human islet amyloid polypeptide J. Biotechnol. 191, 221-227 (2014) http://dx.doi.org/10.1016/j.jbiotec.2014.06.006
Ma P, Schwarten M, Schneider L, Boeske A, Henke N, Lisak D, Weber S, Mohrlüder J, Stoldt M, Strodel B, Methner A, Hoffmann S, Weiergräber OH, Willbold D Interaction of Bcl-2 with the autophagy-related GABAA receptor-associated protein (GABARAP): Biophysical characterization and functional implications J Biol Chem 288, 37204-37215 (2013)
Schünke S, Stoldt M Structural snapshot of cyclic nucleotide binding domains from cyclic nucleotide-sensitive ion channels Biol Chem. 394, 1439-1451 (2013) http://www.ncbi.nlm.nih.gov/pubmed/24021595
Koenig BW, Schünke S, Stoldt M, Willbold D NMR methods for the determination of protein-ligand interactions. Protein-Ligand Interactions" (Editor: H. Gohlke) (series "Methods and Principles in Medicinal Chemistry"), Wiley-VCH; ISBN: 3-527-32966-8, (2012)
Lecher J, Schwarz CKW, Stoldt M, Smits SHJ, Willbold D, Schmitt L RTX toxin transporters tether its substrate prior to secretion via the unique function of its N- terminal domain. Structure 20, 1778-1787 (2012)
Sun N, Hartmann R, Lecher J, Stoldt M, Funke SA, Gremer L, Ludwig H-H, Demuth H-U, Kleinschmidt M, Willbold D Structural analysis of the pyroglutamate modified isoform of the Alzheimer's disease related beta-amyloid using NMR spectroscopy. J. Pept. Science 18, 691-695 (2012)
Lecher J, Stoldt M, Schwarz CKW, Smits SHJ, Schmitt L, Willbold D ¹H, ¹⁵N and ¹³C resonance assignment of the N-terminal C39 peptidase-like domain of the ABC transporter Haemolysin B (HlyB). Biomol. NMR Assign. 53, 199-201 (2011)
Schünke S, Stoldt M, Lecher J, Kaupp UB, Willbold D Structural insights into conformational changes of a cyclic nucleotide-binding domain in solution from Mesorhizobium loti K1 channel. Proc. Natl. Acad. Sci. USA 108, 6121-6126 (2011)
Ma P, Mohrlüder J, Schwarten M, Stoldt M, Singh SK, Hartmann R, Pacheco V, Willbold D Preparation of a functional GABARAP-lipid conjugate in nanodiscs and its investigation by solution NMR spectroscopy Chembiochem 11, 1967-1970 (2010)
Schünke S, Lecher J, Stoldt M, Kaupp UB, Willbold D Resonance assignments of the nucleotide-free wildtype MloK1 cyclic nucleotide-binding domain. Biomol. NMR Assign. 4, 147-150 (2010)
Schwarten M, Stoldt M, Mohrlüder J, Willbold D Solution structure of Atg8 reveals conformational polymorphism of the N-terminal domain Biochem Biophys Res Commun 395, 426-431 (2010)
Feuerstein SE, Pulvermüller A, Hartmann R, Granzin J, Stoldt M, Henklein P, Ernst OP, Heck M, Willbold D, Koenig BW Helix formation in Arrestin accompanies recognition of photoactivated Rhodopsin. Biochemsitry 48, 10733-42 (2009)
Schünke S, Stoldt M, Novak K, Kaupp UB, Willbold D Solution structure of the M.loti K1 channel cyclic nucleotide binding domain in complex with cAMP. EMBO Rep. 10, 729-735 (2009)
Schwarten M, Mohrlüder J, Ma P, Stoldt M, Thielmann Y, Stangler T, Hersch N, Hoffmann B, Merkel R, Willbold D Nix directly binds to GABARAP: a possible crosstalk between apoptosis and autophagy Autophagy 5, 690-698 (2009)
Schwarten M, Stoldt M, Mohrlüder J, Willbold D Sequence-specific 1H, 13C, and 15N resonance assignment of the autophagy-related protein Atg8 Biomol NMR Assign 3, 137-139 (2009)
Wittlich M, Koenig BW, Stoldt M, Schmidt H, Willbold D NMR structural characterization of HIV-1 virus protein U cytoplasmic domain in the presence of dodecylphosphatidylcholine micelles. FEBS J. 276, 6560-75 (2009)
Schmidt H, Hoffmann S, Tran T, Stoldt M, Stangler T, Wiesehan K, Willbold D Solution structure of a Hck SH3 domain ligand complex reveals novel interaction modes. J. Mol. Biol. 365, 1517-1532 (2007)
Schünke S, Novak K, Stoldt M, Kaupp UB, Willbold D Resonance assignment of the cyclic nucleotide binding domain from a cyclic nucleotide-gated K+ channel in complex with cAMP. Biomol. NMR Assign. 1, 179-181 (2007)
Batra-Safferling R, Abaraca-Heidemann K, Körschen HG, Tziatzios C, Stoldt M, Budyak I, Willbold D, Schwalbe H, Klein-Seetharaman J, Kaupp UB Glutamic acid-rich proteins of rod photoreceptors are natively unfolded. J Biol Chem 281, 1449-1460 (2006)
Hänel K, Stangler T, Stoldt M, Willbold D Solution structure of the X4 protein coded by the SARS related coronavirus reveals an immunoglobulin like fold and suggests a binding activity to integrin I domains. J. Biomed. Sci. 13, 281-293 (2006)
Stoldt M, Kupce E, Rehm BHA, Görlach M Backbone resonance assignemnt of an aminogycoside-3'-phosphotransferase type IIa. J. Biomol. NMR 28, 93-94 (2004)
Wiesehan K, Buder K, Linke RP, Patt S, Stoldt M, Unger E, Schmitt B, Bucci E and Willbold D Selection of D-amino-acid peptides that bind to Alzheimer's disease amyloid peptide Abeta(1-42) by mirror image phage display. ChemBioChem 4, 748-753 (2003)
Mueller F, Sommer I, Baranov P, Matadeen R, Stoldt M, Wöhnert J, Görlach M, van Heel M, Brimacombe R The 3D arrangement of the 23 S and 5 S rRNA in the Escherichia coli 50 S ribosomal subunit based on a cryo-electron microscopic reconstruction at 7.5 A resolution. J Mol Biol. 298, 35-59 (2000)
Stoldt M, Wöhnert J, Ohlenschläger O, Görlach M, Brown LR The NMR structure of the 5S rRNA E-domain-protein L25 complex shows preformed and induced recognition. EMBO J. 18, 6508-6521 (1999)
Wöhnert J, Dingley AJ, Stoldt M, Görlach M, Grzesiek S, Brown LR Direct identification of NH...N hydrogen bonds in non-canonical base pairs of RNA by NMR spectroscopy. Nucleic Acids Res. 27, 3104-3110 (1999)
Stoldt M, Wöhnert J, Görlach M, Brown LR The NMR structure of Escherichia coli ribosomal protein L25 shows homology to general stress proteins and glutaminyl-tRNA synthetases. EMBO J. 17, 6377-6384 (1998)
Wöhnert J, Brenn J, Stoldt M, Aleksiuk O, Grynszpan F, Thondorf I, Biali SE Conformation and stereodynamics of monodioxamethylene calix[4]arene derivatives J. Org. Chem. 63, 3866-3874 (1998)
Stoldt M, Porzel A, Adam G, Brandt W Side chain conformation of the Growth-promoting phytohormones brassinolide and 24-epibrassionolide Magn. Reson. Chem. 35, 629-636 (1997)
Brandt W, Stoldt M, Schinke H The mu- and delta-opioid pharmacophore conformations of cyclic beta-casomorphin analogues indicate docking of the Phe3 residue to different domains of the opioid receptors J Comput Aided Mol Des 10, 201-212 (1996)
