Welcome to Institut für Physikalische Biologie

The function of each cell and each organism decisively depends on the dynamic interactions between biological macromolecules and on their correct three-dimensional structure. Faulty interaction and incorrectly folded structures eventually lead to diseases and ageing. Our aim is to understand these interactions and to determine the three-dimensional structure of the protein complexes involved in decisive cellular processes - if possible, in atomic resolution. Beyond that, we develop novel methods for the early diagnosis and treatment of neurodegenerative diseases, with a strong focus on Alzheimer's dementia. undefined[more]

Prof. Dr. Dieter Willbold is the director of the institute. His Department focusses on Modelling Systems, Virus-Host-Interaction and Neurofunction/Neurodegeneration. undefined[more] The Department of Prof. Dr. Henrike Heise is developing new methods in the field of solid state NMR-Spektroscopy.

A close cooperation exists with the undefinedInstitute of Complex Systems (ICS-6: Structural Biochemistry) at Forschungszentrum Jülich, which is also headed by Prof. Dr. Willbold. Together, the two institutes run the undefinedBiomolecular NMR-Center in Jülich.

A close cooperation exists with the undefinedInstitute of Complex Systems (ICS-6: Structural Biochemistry) at Forschungszentrum Jülich, which is also headed by Prof. Dr. Willbold.

Together, the two institutes run the Biomolecular NMR-Center in Jülich.

08.03.17 Erwin Niehaus-Preis for Alexander Büll

Jun.-Prof. Dr. Alexander Büll (34) has been awarded the Erwin Niehaus-Preis by the Alzheimer Forschung Initiative e.V. (AFI). With the award comes 40.000 Euro in funding for a research project on artificial amyloid plaques. (more in German)

24.02.17 Fluorescent Proteins in New Colours

Researchers from Jülich and Düsseldorf have succeeded in taking an important step towards making LOV proteins more usable for future biotechnological applications. These glowing protein molecules regulate many light-dependent processes in plant and bacterial cells. They also have favourable properties for various light-based applications. This means they could serve as a new class of molecular markers to analyse cellular processes using fluorescence microscopy. more (in German)

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