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Targeting HSP90 dimerization via the C terminus is effective in imatinib-resistant CML and lacks the heat shock response.
Blood 132(3), 307-320 (2018)
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Structure and interaction of Corynebacterium pseudotuberculosis cold shock protein A with Y-box single-stranded DNA fragment
FEBS J 285, 372-390 (2018)
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Inhibition of amyloid Aβ aggregation by high pressures or specific d-enantiomeric peptides.
Chem Commun (Camb). 54(26), 3294-3297 (2018)
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Zika virus NS2B/NS3 proteinase: A new target for an old drug - Suramin a lead compound for NS2B/NS3 proteinase inhibition.
Antiviral Res. 160, 118-125 (2018)
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Transcriptome-wide analysis uncovers the targets of the RNA-binding protein MSI2 and effects of MSI2's RNA-binding activity on IL-6 signaling
J. Biol. Chem. 293, 15359-15369 (2018)
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Aβ oligomer eliminating compounds interfere successfully with pEAβ (3â42) induced motor neurodegenerative phenotype in transgenic mice
Neuropeptides 67, 27-35 (2018)
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Comprehensive Characterization of the Pyroglutamate Amyloid-β Induced Motor Neurodegenerative Phenotype of TBA2.1 Mice.
J Alzheimers Dis. 63(1), 115-130 (2018)
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Mechanistic Basis of the Fast Dark Recovery of the Short LOV Protein DsLOV from Dinoroseobacter shibae.
Biochemistry 57, 4833â4847 (2018)
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Spectroscopic characterization of the Co-substituted C-terminal domain of Rubredoxin-2
Biological Chemistry 399, 787-798 (2018)
https://doi.org/10.1515/hsz-2018-0142
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Origin of metastable oligomers and their effects on amyloid fibril self-assembly
Chem. Sci. 9, 5937-5948 (2018)
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Advancements of the sFIDA method for oligomer-based diagnostics of neurodegenerative diseases
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Elucidating the multi-targeted anti-amyloid activity and enhanced islet amyloid polypeptide binding of β-wrapins
Comput. Chem. Eng. 116, 322-332 (2018)
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Asp1 Bifunctional Activity Modulates Spindle Function via Controlling Cellular Inositol Pyrophosphate Levels in Schizosaccharomyces pombe
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Small-angle X-ray scattering study of the kinetics of light-dark transition in a LOV protein
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A d-enantiomeric peptide interferes with heteroassociation of amyloid-β oligomers and prion protein
J. Biol. Chem. 293, 15748-15764 (2018)
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In Vitro Reconstitution of the Highly Active and Natively Folded Recombinant Human Superoxide Dismutase 1 Holoenzyme
ChemistrySelect 3, 7627-7632 (2018)
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In Vitro Potency and Preclinical Pharmacokinetic Comparison of All-D-Enantiomeric Peptides Developed for the Treatment of Alzheimer's Disease.
J Alzheimers Dis 64(3), 859-873 (2018)
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Proline restricts loop 1 conformation of the high affinity WW domain from human Nedd4-1 to a ligand binding-competent type 1 beta-turn
J Phys Chem B 122, 4219-4230 (2018)
https://doi.org/10.1021/acs.jpcb.7b11637
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Conformational sampling of the intrinsically disordered C-terminal tail of DERA is important for enzyme catalysis
ACS Catal 8, 3971-3984 (2018)
https://doi.org/10.1021/acscatal.7b04408
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Viroid research and its significance for RNA technology and basic biochemistry.
Nucleic Acids Res. 46, 10563-10576 (2018)
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DNP-Enhanced MAS NMR: A Tool to Snapshot Conformational Ensembles of α-Synuclein in Different States
Biophys. J. 114, 1614-1623 (2018)
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Structural insights from lipid-bilayer nanodiscs link α-Synuclein membrane-binding modes to amyloid fibril formation
Commun. Biol. 1, 44 (2018)
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α-Synuclein aggregation monitored by Thioflavin T fluorescence assay
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Biophysical insights from a single chain camelid antibody directed against the disrupted in schizophrenia 1 protein
PLoS One 13, e0191162 (2018)
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Stoichiometric Zn2+ interferes with the self-association of Aβ42: Insights from size distribution analysis.
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