Welcome to the pages of the Tamgüney research group!
We study neurodegenerative diseases such as Parkinson's and Alzheimer's, which affect the brain and lead to motor deficits and/or cognitive impairment and dementia. These diseases are characterized by the misfolding and aggregation of specific neuronal proteins, such as α-synuclein in Parkinson's disease or amyloid-β and tau in Alzheimer's disease, which cause neuronal damage and loss. The focus of our research work is to gain a better understanding of the cellular and systemic spread of toxic protein aggregates, to develop a diagnostic laboratory test for the early detection of Parkinson's and Alzheimer's disease, and to develop a vaccine to protect against Parkinson's disease.
On the following pages you can get an impression of our research work.