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Publikationen 2022

  • Bartl, J. and Zanini, M. and Bernardi, F. and Forget, A. and Blümel, L. and Talbot, J. and Picard D, Qin N, Cancila G, Gao Q, Nath S, Koumba IM, Wolter M, Kuonen F, Langini M, Beez, T, Munoz C, Pauck D, Marquardt V, Yu H, Souphron J, Korsch M, Mölders C, Berger D, Göbbels S, Meyer FD, Scheffler B, Rotblat B, Diederichs S, Ramaswamy V, Suzuki H, Oro A, Stühler K, Stefanski A, Fischer U, Leprivier G, Willbold D, Steger G, Buell A, Kool M, Lichter P, Pfister SM, Northcott PA, Taylor MD, Borkhardt A, Reifenberger G, Ayrault O, Remke M 
    The HHIP-AS1 lncRNA promotes tumorigenicity through stabilization of dynein complex 1 in human SHH-driven tumors. 
    Nat. Commun . 13, 4061 (2022) 
    https://doi.org/10.1038/s41467-022-31574-z  
  • Borggräfe J, Etzkorn M 
    Solution NMR Spectroscopy as a Tool to Study DNAzyme Structure and Function. 
    Methods in Molecular Biology 2439, 131-151 (2022) 
    https://doi.org/10.1007/978-1-0716-2047-2_10  
  • Borggräfe J, Victor J, Rosenbach H, Viegas A, Gertzen CGW, Wuebben C, Kovacs H, Gopalswamy M, Riesner D, Steger G, Schiemann O, Gohlke H, Span I, Etzkorn M  
    Time-resolved structural analysis of an RNA-cleaving DNA catalyst. 
    Nature 601, 144-149 (2022) 
    https://doi.org/10.1038/s41586-021-04225-4  
  • Braczynski AK, Sevenich M, Gering I, Kupreichyk T, Agerschou ED, Kronimus Y, Habib P, Stoldt M, Willbold D, Schulz JB, Bach JP, Falkenburger BH, Hoyer W 
    Alpha-synuclein-specific naturally occurring antibodies inhibit aggregation in vitro and in vivo 
    Biomolecules 12, 469 (2022) 
    https://doi.org/10.3390/biom12030469  
  • Brown H, Chung M, Üffing A, Batistatou N, Tsang T, Doskocil S, Mao W, Willbold D, Bast RC Jr, Lu Z, Weiergräber OH, Kritzer JA 
    Structure-Based Design of Stapled Peptides That Bind GABARAP and Inhibit Autophagy 
    J Am Chem Soc 144, 14687-14697 (2022) 
    https://doi.org/10.1021/jacs.2c04699  
  • Florian Bleffert, Joachim Granzin, Muttalip Caliskan, Stephan N Schott-Verdugo, Meike Siebers, Björn Thiele, Laurence Rahme, Sebastian Felgner, Peter Dörmann, Holger Gohlke* , Renu Batra-Safferling*, Karl-Erich Jaeger, Filip Kovacic* 
    Structural, mechanistic, and physiological insights into phospholipase A-mediated membrane phospholipid degradation in Pseudomonas aeruginosa. 
    eLife 11, e72824 (2022) 
    https://doi.org/10.7554/eLife.72824  
  • Huwa N, Weiergräber OH, Fejzagić AV, Kirsch C, Schaffrath U, Classen T 
    The Crystal Structure of the Defense Conferring Rice Protein OsJAC1 Reveals a Carbohydrate Binding Site on the Dirigent-like Domain 
    Biomolecules 12, 1126 (2022) 
    https://doi.org/10.3390/biom12081126  
  • Kass B, Schemmert S, Zafiu C, Pils M, Bannach O, Kutzsche J, Bujnicki T, Willbold D. 
    Aβ oligomer concentration in mouse and human brain and its drug-induced reduction ex vivo. 
    Cell Rep Med. 3(5):100630, (2022) 
    https://doi.org/10.1016/j.xcrm.2022.100630  
  • Kirchgässler N, Rosenbach H, Span I 
    Stability and Activity of the 10–23 DNAzyme Under Molecular Crowding Conditions. 
    Methods in Molecular Biology 2439, 79-89 (2022) 
    https://doi.org/10.1007/978-1-0716-2047-2_6  
  • Maity D, Oh Y, Gremer L, Hoyer W, Magzoub M, Hamilton AD 
    Cucurbit[7]uril inhibits islet amyloid polypeptide aggregation by targeting N terminus hot segments and attenuates cytotoxicity 
    Chemistry , e202200456 (2022) 
    https://doi.org/10.1002/chem.202200456  
  • Matoušek J, Steger G 
    The Splicing Variant TFIIIA-7ZF of Viroid-Modulated Transcription Factor IIIA Causes Physiological Irregularities in Transgenic Tobacco and Transient Somatic Depression of “Degradome” Characteristic for Developing Pollen. 
    Cells 11, (2022) 
    https://doi.org/10.3390/cells11050784  
  • Rosenbach H, Span I 
    Obtaining Crystals of Nucleic Acids in Complex with the Protein U1A Using the Soaking Method 
    Methods in Molecular Biology 2439, 105-115 (2022) 
    https://doi.org/10.1007/978-1-0716-2047-2_8  
  • Rosenbach H, Steger G 
    Fluorescence-Based Kinetic Measurements for RNA-Cleaving DNAzymes 
    Methods in Molecular Biology 2439, 65-77 (2022) 
    https://doi.org/10.1007/978-1-0716-2047-2_5  
  • Sevenich M, Honold D, Willuweit A, Kutzsche J, Mohrlüder J, Willbold D. 
    Development of an α-synuclein fibril and oligomer specific tracer for diagnosis of Parkinson's disease, dementia with Lewy bodies and multiple system atrophy.  
    Neurochem Int. 161, 105422 (2022) 
    https://doi.org/10.1016/j.neuint.2022.105422  
    https://pubmed.ncbi.nlm.nih.gov/36252819/  
  • Steger G 
    Predicting the Structure of a Viroid: Structure, Structure Distribution, Consensus Structure, and Structure Drawing 
    Methods in Molecular Biology 2316, 331-371 (2022) 
    https://doi.org/10.1007/978-1-0716-1464-8_26  
  • Steger G, Rosenbach H, Span I (Eds) 
    DNAzymes 
    Methods in Molecular Biology 2439, (2022) 
    https://link.springer.com/book/10.1007/978-1-0716-2047-2  
  • Steger G, Victor J 
    Design of a DNAzyme 
    Methods in Molecular Biology 2439, 47-63 (2022) 
    https://doi.org/10.1007/978-1-0716-2047-2_4  
  • Törner R, Kupreichyk T, Gremer L, Debled EC, Fenel D, Schemmert S, Gans P, Willbold D, Schoehn G, Hoyer W, Boisbouvier J 
    Structural basis for the inhibition of IAPP fibril formation by the co-chaperonin prefoldin 
    Nat Commun 13, 2363 (2022) 
    https://doi.org/10.1038/s41467-022-30042-y  
  • Weiergräber OH, Petrović D, Kislat A, Pattky M, Fabig J, Batra-Safferling R, Schulte am Esch J, Hänel K, Huhn C, Strodel B, Homey B, Willbold D 
    Structure and Dynamics of Human Chemokine CCL16—Implications for Biological Activity 
    Biomolecules 12, 1588 (2022) 
    https://doi.org/10.3390/biom12111588  
  • Wüsthoff K, Steger G 
    Conserved Motifs and Domains in Members of Pospiviroidae 
    Cells 11, 230 (2022) 
    https://doi.org/10.3390/cells11020230  
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