Borggräfe J, Gertzen CGW, Viegas A, Gohlke H, Etzkorn M The architecture of the 10-23 DNAzyme and its implications for DNA-mediated catalysis FEBS Journal 290, 2011-2021 (2023) https://doi.org/10.1111/febs.16698
Borggräfe J, Etzkorn M Solution NMR Spectroscopy as a Tool to Study DNAzyme Structure and Function. Methods in Molecular Biology 2439, 131-151 (2022) https://doi.org/10.1007/978-1-0716-2047-2_10
Borggräfe J, Victor J, Rosenbach H, Viegas A, Gertzen CGW, Wuebben C, Kovacs H, Gopalswamy M, Riesner D, Steger G, Schiemann O, Gohlke H, Span I, Etzkorn M Time-resolved structural analysis of an RNA-cleaving DNA catalyst. Nature 601, 144-149 (2022) https://doi.org/10.1038/s41586-021-04225-4
Glueck D, Grethen A, Das M, Mmeka OP, Perez Patallo E, Meister A, Rajender R, Ahlhelm J, Kins S, Raeschle M, Victor J, Etzkorn M, Koeck Z, Bernhard F, Babalola JO, Vargas C, Keller S Electroneutral polymer nanodiscs enable interference-free probing of membrane proteins in a lipid-bilayer environment Small 18, 2202492 (2022) https://doi.org/10.1002/smll.202202492
Gopalswamy M, Kroeger T, Bickel D, Frieg B, Akter S, Schott-Verdugo S, Viegas A, Pauly T, Mayer M, Przibilla J, Reiners J, Nagel-Steger L, Smits SHJ, Groth G, Etzkorn M, Gohlke H Biophysical and pharmacokinetic characterization of a small-molecule inhibitor of RUNX1/ETO tetramerization with anti-leukemic effects. Sci Rep 12, 1-18 (2022) https://doi.org/10.1038/s41598-022-17913-6
Dubey A, Stoyanov N, Viennet T, Chhabra S, Elter S, Borggräfe J, Viegas A, Nowak RP, Burdzhiev N, Petrov O, Fischer ES, Etzkorn M, Gelev V, Arthanari H Local Deuteration Enables NMR Observation of Methyl Groups in Proteins from Eukaryotic and Cell-Free Expression Systems Angew. Chem. Int. Ed. 60, 13783 (2021) https://doi.org/10.1002/anie.202016070
Rosenbach H, Borggräfe J, Victor J, Wuebben C, Schiemann O, Hoyer W, Steger G, Etzkorn M, Span I Influence of monovalent metal ions on metal binding and catalytic activity of the 10–23 DNAzyme Biological Chemistry 402, 99-111 (2021) https://doi.org/10.1515/hsz-2020-0207
Rosenbach H, Victor J, Borggräfe J, Biehl R, Steger G, Etzkorn M, Span I. Expanding crystallization tools for nucleic acid complexes using U1A protein variants Journal of Structural Biology 210, 107480 (2020) https://doi.org/10.1016/j.jsb.2020.107480
Rosenbach H, Victor J, Etzkorn M, Steger G, Riesner D, Span I Molecular Features and Metal Ions that Influence 10-23 DNAzyme Activity Molecules 25, 3100 (2020) https://doi.org/10.3390/molecules25133100 Special Issue "Advances in Catalytic DNA"
Rösener NS, Gremer L, Wördehoff MM, Kupreichyk T, Etzkorn M, Neudecker P, Hoyer W Clustering of human prion protein and α-synuclein oligomers requires the prion protein Nterminus Commun. Biol. 3, 365 (2020) https://doi.org/10.1038/s42003-020-1085-z
Viegas A, Dollinger P, Verma N, Kubiak J, Viennet T, Seidel CAM, Gohlke H, Etzkorn M, Kovacic F, Jaeger KE Structural and dynamic insights revealing how lipase binding domain MD1 of Pseudomonas aeruginosa foldase affects lipase activation Sci Rep 10, 3578 (2020) https://doi.org/10.1038/s41598-020-60093-4
Viegas A, Yin DM, Borggräfe J, Viennet T, Falke M, Schmitz A, Famulok M, Etzkorn M Molecular Architecture of a Network of Potential Intracellular EGFR Modulators: ARNO, CaM, Phospholipids, and the Juxtamembrane Segment Structure 28, 1-9 (2020) https://doi.org/10.1016/j.str.2019.11.001
Falke M, Victor J, Wördehoff MM, Peduzzo A, Zhang T, Schröder GF, Buell AK, Hoyer W, Etzkorn M α-Synuclein-derived lipoparticles in the study of α-synuclein amyloid fibril formation Chem Phys Lipids 220, 57-65 (2019) https://doi.org/10.1016/j.chemphyslip.2019.02.009
Porta N, Zaschke-Kriesche J, Frieg J, Gopalswamy M, Zivkovic A, Etzkorn M, Stark H, Smits S, Gohlke H Small-molecule inhibitors of nisin resistance protein NSR from the human pathogen Streptococcus agalactiae Bioorg Med Chem 27, 115079 (2019) https://doi.org/10.1016/j.bmc.2019.115079
Viennet T, Bungert-Pümke S, Elter S, Viegas A, Fahlke C, Etzkorn M Reconstitution and NMR characterization of the ion-channel accessory subunit barttin in detergents and lipid-bilayer nanodiscs Frontiers in Molecular Biosciences 6, 13 (2019) https://doi.org/10.3389/fmolb.2019.00013
Uluca B, Viennet T, Petrovic D, Shaykhalishahi H, Weirich F, Gönülalan A, Strodel B, Etzkorn M, Hoyer W, Heise H DNP-Enhanced MAS NMR: A Tool to Snapshot Conformational Ensembles of α-Synuclein in Different States Biophys. J. 114, 1614-1623 (2018) https://doi.org/10.1016/j.bpj.2018.02.011
Bronder AM, Bieker A, Elter S, Etzkorn M, Haeussinger D, Oesterhelt F Oriented membrane protein reconstitution into tethered lipid membranes for AFM Force Spectroscopy Biophys. J. 111, 1925-1934 (2016) http://dx.doi.org/10.1016/j.bpj.2016.08.051
Viegas A, Viennet T, Etzkorn M The power, pitfalls and potential of the nanodisc system for NMR-based studies Biol. Chem. 397, 1335–1354 (2016) https://doi.org/10.1515/hsz-2016-0224
Viegas A, Viennet T, Yu TY, Schumann F, Bermel W, Wagner G, Etzkorn M UTOPIA NMR: activating unexploited magnetization using interleaved low-gamma detection. J. Biomol. NMR 64, 9-15 (2016) http://dx.doi.org/10.1007/s10858-015-0008-7
Viennet T, Viegas A, Kuepper A, Arens S, Gelev V, Petrov O, Grossmann TN, Heise H, Etzkorn M Selective Protein Hyperpolarization in Cell Lysates Using Targeted Dynamic Nuclear Polarization Angew. Chem. Int. Ed. 55, 10746–10750 (2016) http://dx.doi.org/10.1002/anie.201603205 (selected as inside cover article)
Elter S, Raschle T, Arens S, Viegas A, Gelev V, Etzkorn M, Wagner G The use of amphipols for NMR structural characterization of 7-TM proteins J. Membr. Biol. 247, 957-964 (2014) http://dx.doi.org/10.1007/s00232-014-9669-5
Etzkorn M, Zoonens M, Catoire LJ, Popot JL, Hiller S How Amphipols Embed Membrane Proteins: Global Solvent Accessibility and Interaction with a Flexible Protein Terminus J. Membr. Biol. 247, 965-970 (2014) http://dx.doi.org/10.1007/s00232-014-9657-9
Yi T, Zhai B, Yu Y, Kiyotsugu Y, Raschle T, Etzkorn M, Seo HC, Nagiec M, Luna RE, Reinherz EL, Blenis J, Gygi SP, Wagner G Quantitative phosphoproteomic analysis reveals system-wide signaling pathways downstream of SDF-1/CXCR4 in breast cancer stem cells PNAS 111(21), E2182-E2190 (2014) http://dx.doi.org/10.1073/pnas.1404943111 http://dx.doi.org/10.1073/pnas.1405991111 See also PNAS highlight commentary (follow second link)
Etzkorn M, Raschle T, Hagn F, Gelev V, Rice A, Walz T, Wagner G Cell-Free Expressed Bacteriorhodopsin in Different Soluble Membrane Mimetics: Biophysical Properties and NMR Accessibility. Structure 21, 394-401 (2013) http://dx.doi.org/10.1016/j.str.2013.01.005
Hagn F, Etzkorn M, Raschle T, Wagner G Optimized phospholipid bilayer nanodiscs facilitate high-resolution structure determination of membrane proteins J. Am. Chem. Soc 135, 1919-1925 (2013) http://dx.doi.org/10.1021/ja310901f (See also Science Editor's Choice:
http://dx.doi.org/10.1126/science.339.6123.1013-a )
Müller H, Etzkorn M, Heise H Solid-State NMR Spectroscopy of Proteins. Top. Curr. Chem. in press, (2013)
Etzkorn M, Böckmann A, Baldus M Kinetic analysis of protein aggregation monitored by real-time 2D solid-state NMR J. biomol. NMR 49, 121-129 (2011) http://dx.doi.org/10.1007/s10858-011-9468-6
Bardiaux B, Favier A, Etzkorn M, Baldus M, Böckmann A, Nilges M, Malliavin T: Simultaneous use of solution, solid-state NMR and X-ray crystallography to study the conformational landscape of the Crh protein during oligomerization and crystallization. Adv. Appl. Bioinf. Chem. 3, 25-38 (2010)
Etzkorn M, Seidel K, Li L, Martell S, Engelhard M, Baldus M Complex Formation and Light Activation in Membrane Embedded Sensory Rhodopsin II as Seen by Solid-State NMR Spectroscopy. Structure 10, 293-300 (2010) http://dx.doi.org/10.1016/j.str.2010.01.011
Kneuper H, Scheu PD, Etzkorn M, Sevvana M, Dünnwald P, Becker S, Baldus M, Griesinger C, Unden G Sensing Ligands by Periplasmic Sensing Histidine Kinases with Sensory PAS Domains. Sensory Mechanisms in Bacteria; Caister Academic Press, (2010)
Raschle T, Hiller S, Etzkorn M, Wagner G Non-micellar systems for solution NMR spectroscopy of membrane proteins. Curr. Opin. Struct. Biol. 20, 471-479 (2010) http://dx.doi.org/10.1016/j.sbi.2010.05.006
Schneider R, Etzkorn M, Giller K, Daebel V, Eisfeld J, Zweckstetter M, Griesinger C, Becker S, Lange A The Native Conformation of the Human VDAC1 N Terminus Angew. Chem. Int. Ed. 49, 1882-1885 (2010) http://dx.doi.org/10.1002/anie.200906241
Schneider R, Seidel K, Etzkorn M, Lange A, Becker S, Baldus M Probing molecular motion by double-quantum (13C,13C) solid-state NMR spectroscopy: application to ubiquitin. J. Am. Chem. Soc 132, 223-233 (2010) http://dx.doi.org/10.1021/ja906283h
Ader C, Schneider R, Seidel K, Etzkorn M, Becker S, Baldus M Structural rearrangements of membrane proteins probed by water-edited solid-state NMR spectroscopy. J. Am. Chem. Soc 131, 170-176 (2009) http://dx.doi.org/10.1021/ja806306e
Seidel K, Etzkorn M, Schneider R, Ader C, Baldus M Comparative Analysis of NMR Chemical Shift Predictions for Proteins in the Solid Phase. Solid State Nucl. Magn. Res. 35, 235-242 (2009) http://dx.doi.org/10.1016/j.ssnmr.2008.12.008
Etzkorn M, Kneuper H, Dünnwald P, Vijaian V, Griesinger C, Becker S, Unden G, Baldus M Plasticity of the PAS domain and a potential role for signal transduction in the histidine kinase DcuS. Nat. Struct. Mol. Biol. 15, 1031-1039 (2008) http://dx.doi.org/10.1038/nsmb.1493 (selected as "Article of the month")
Gardiennet C, Loquet A, Etzkorn M, Heise H, Baldus M, Böckmann A Structural constraints for the Crh protein from solid-state NMR. J. biomol. NMR 4035, 239-250 (2008) http://dx.doi.org/10.1007/s10858-008-9229-3
Ader C, Schneider R, Seidel K, Etzkorn M, Baldus, M Magic-angle-spinning NMR spectroscopy applied to small molecules and peptides in lipid bilayers. Biochem. Soc. Trans. 35, 991-995 (2007) http://dx.doi.org/10.1042/BST0350991
Etzkorn M, Böckmann A, Penin F, Riedel D, Baldus M Characterization of folding intermediates of a domain-swapped protein by solid-state NMR spectroscopy. J. Am. Chem. Soc 129, 169-175 (2007) http://dx.doi.org/10.1021/ja066469x
Etzkorn M, Martell S, Andronesi OC, Seidel K, Engelhard M, Baldus M Secondary structure and topology of a seven-helix receptor in native membranes studied by solid-state NMR. Angew. Chem. Int. Ed. 46, 459-462 (2007) http://dx.doi.org/10.1002/anie.200602139 (selected as "Cover article")
Heise H, Seidel K, Etzkorn M, Becker S, Baldus M 3D MAS Solid-state NMR spectroscopy for resonance assignment and structure elucidation of proteins. Novel pulse schemes and sensitivity considerations. J. Magn. Res. 173, 65-74 (2005) http://dx.doi.org/10.1016/j.jmr.2004.11.020
Seidel K, Etzkorn M, Heise H, Becker S, Baldus M High-resolution solid-state NMR studies on uniformly [13C,15N]-labeled ubiquitin. ChemBioChem 6, 1638-1647 (2005) http://dx.doi.org/10.1002/cbic.200500085
Seidel K, Etzkorn M, Sonnenberg L, Griesinger C, Sebald A, Baldus M Studying 3D structure and dynamics by high resolution solid-state NMR: Application to L-Tyrosine-Ethylester. J. Phys. Chem. A 109, 2436-2442 (2005) http://dx.doi.org/10.1021/jp045605m
Etzkorn M, Böckmann A, Lange A, Baldus M Probing molecular interfaces using 2D magic-angle-spinning NMR on protein mixtures with di¬fferent uniform labeling. J. Am. Chem. Soc 126, 14746-14751 (2004) http://dx.doi.org/10.1021/ja0479181
