Zum Inhalt springen Zur Suche springen

Publikationen

  • Pils M, Dybala A, Schaffrath S, Rehn F, Kutzsche J, Blömeke L, Tusche M, Özdüzenciler P, Bujnicki T, Kraemer-Schulien V, Gramespacher H, Schmieschek MHT, Barbe MT, Onur ÖA, Fink GR, Tamgüney G, Bannach O, Willbold D
    Elevated Aβ aggregates in feces from Alzheimer’s disease patients: a proof-of-concept study
    Alzheimer's Research & Therapy, accepted (2024)
    https://doi.org/10.

  • Schulz CM, Agerschou ED, Gardon L, Alexander M, Stoldt M, Heise H, Tamgüney G, Hoyer W
    Disordered regions of inhibitor-bound α-synuclein suppress seed-induced fibril nucleation in cells
    Cell Reports Physical Science, pre-accepted (2024)
    https://doi.org/10.

  • Weber TM, Özdüzenciler P, Tamgüney G, Pietruszka J
    Utilization of a Branched Late-Stage Clickable Biotinylated Chassis on the Example of a Pittsburgh B Analog
    Organic Letters, 26, 6771-6775 (2024)
    https://doi.org/10.1021/acs.orglett.4c02527

  • Holtz AV, Fink A, Tamgüney G, Doblhammer G
    Colonoscopy and subsequent risk of Parkinson’s disease
    J Parkinsons Dis, 14, 747-760 (2024)
    https://doi.org/10.3233/JPD-240017

  • Flores-Fernandez JM, Pesch V, Sriraman A, Chimal Juarez E, Amidian S, Wang X, Duckering C, Fang A, Reithofer S, Ma L, Cortez LM, Sim VL, Tamgüney G, Wille H
    Rational design of structure-based vaccines targeting misfolded alpha-synuclein conformers of Parkinson’s disease and related disorders
    Bioeng Transl Med, 9, e10665 (2024)
    https://doi.org/10.1002/btm2.10665

  • Reineke B, Paulus I, Löffelsend S, Yu CH, Vinogradov D, Meyer A, Hazur J, Röder J, Vollmer M, Tamgüney G, Hauschild S, Boccaccini AR, Groll J, Förster S
    On-chip fabrication and in-flow 3D-printing of microgel constructs: from chip to scaffold materials in one integral process
    Biofabrication, 16 (2024)
    https://doi.org/10.1088/1758-5090/ad3318

  • Pesch V, Flores-Fernandez JM, Reithofer S, Ma L , Özdüzenciler P, Busch Y, Sriraman A, Wang YL, Amidian S, Kroepel CVM, Müller L, Lien Y, Rudtke O, Frieg B, Schröder GF, Wille H, Tamgüney G
    Vaccination with structurally adapted fungal protein fibrils induces immunity to Parkinson's disease
    Brain, 147, 1644-1652 (2024)
    https://doi.org/10.1093/brain/awae061

  • Kuzkina A, Rößle J, Seger A, Panzer C, Kohl A, Maltese V, Musacchio T, Blaschke S, Tamgüney G, Kaulitz S, Rak K, Scherzad A, Zimmermann P, Klussmann J, Hackenberg S, Volkmann J, Sommer C, Sommerauer M, Doppler K
    Combining skin and olfactory α-synuclein seed amplification assays (SAA) - towards biomarker-driven phenotyping in synucleinopathies
    NPJ Parkinsons Dis, 9, 14 (2023)
    https://doi.org/10.1038/s41531-023-00519-8

  • Rakuša E, Fink A, Tamgüney G, Heneka MT, Doblhammer G
    Sporadic Use of Antibiotics in Older Adults and the Risk of Dementia: A Nested Case–Control Study Based on German Health Claims Data
    J Alzheimers Dis, 93, 1329-1339 (2023)
    https://doi.org/10.3233/JAD-221153

  • Altendorf T, Gering I, Santiago-Schübel B, Aghabashlou Saisan S, Tamgüney G, Tusche M, Honold D, Schemmert S, Hoyer W, Mohrlüder J, Willbold D
    Stabilization of Monomeric Tau Protein by All D-Enantiomeric Peptide Ligands as Therapeutic Strategy for Alzheimer's Disease and Other Tauopathies
    Int J Mol Sci, 24, 2161 (2023)
    https://doi.org/10.3390/ijms24032161

  • Schaffrath A, Schleyken S, Seger A, Jergas H, Özdüzenciler P, Pils M, Blömeke L, Cousin A, Willbold J, Bujnicki T, Bannach O, Fink GR, Willbold D, Sommerauer M, Barbe MT, Tamgüney G
    Patients with isolated REM-sleep behavior disorder have elevated levels of alpha-synuclein aggregates in stool
    NPJ Parkinsons Dis, 9, 14 (2023)
    https://doi.org/10.1038/s41531-023-00458-4

  • Blömeke L, Pils M, Kraemer-Schulien V, Dybala A, Schaffrath A, Kulawik A, Zack R, Tropea TF, Bujnicki T, Tamgüney G, Weintraub D, Irwin D, Grossman M, Wolk DA, Trojanowski JQ, Bannach O, Chen-Plotkin A, Rehn F, Cousin A, Nischwitz V, Willbold J, Willbold D
    Quantitative detection of α-synuclein and tau oligomers and other aggregates by digital single particle counting
    NPJ Parkinsons Dis, 8, 68 (2022)
    https://doi.org/10.1038/s41531-022-00330-x

  • Lohmann S, Grigoletto J, Bernis ME, Pesch V, Ma L, Reithofer S, Tamgüney G
    Ischemic stroke causes Parkinson's disease-like pathology and symptoms in transgenic mice overexpressing alpha-synuclein
    Acta Neuropathol Commun, 10, 26 (2022)
    https://rdcu.be/cHITe

  • Woerman AL and Tamgüney G
    Body-first Parkinson’s disease and variant Creutzfeldt–Jakob disease – similar or different?
    Neurobiol Dis, 164, 105625 (2022)
    https://doi.org/10.1016/j.nbd.2022.105625

  • Fink A, Doblhammer G, Tamgüney G
    Recurring gastrointestinal infections increase the risk of dementia
    J Alzheimers Dis 84, 797-806 (2021)
    https://doi.org/10.3233/JAD-210316

  • Santur K, Reinartz E, Lien Y, Tusche M, Altendorf T, Sevenich M, Tamgüney G, Mohrlüder J, Willbold D
    Ligand-induced stabilization of the native human superoxide dismutase 1
    ACS Chem Neurosci 12, 2520-2528 (2021)
    https://doi.org/10.1021/acschemneuro.1c00253

  • Van Den Berge N, Ferreira N, Mikkelsen TW, Alstrup AKO, Tamgüney G, Karlsson P, Terkelsen AJ, Nyengaard JR, Jensen PH, Borghammer P
    Ageing promotes pathological alpha-synuclein propagation and autonomic dysfunction in wild-type rats
    Brain 144, 1853-1868 (2021)
    https://doi.org/10.1093/brain/awab061

  • Bernis ME and Tamgüney G
    Bioluminescence imaging of neuroinflammation in a mouse model of Parkinson's disease
    Methods Mol Biol 2081, 147-159 (2020)
    https://doi.org/10.1007/978-1-4939-9940-8_10

  • Van Den Berge N, Ferreira N, Gram H, Mikkelsen TW, Alstrup AKO, Casadei N, Tsung-Pin P, Riess O, Nyengaard JR, Tamgüney G, Jensen PH, Borghammer P
    Evidence for bidirectional and trans-synaptic parasympathetic and sympathetic propagation of alpha-synuclein in rats
    Acta Neuropathol 138, 535-550 (2019)
    https://doi.org/10.1007/s00401-019-02040-w

  • Lohmann S, Bernis ME, Babila JT, Ziemski A, Grigoletto J, Tamgüney G
    Oral and intravenous transmission of α-synuclein fibrils to mice
    Acta Neuropathol 138, 515-533 (2019)
    https://doi.org/10.1007/s00401-019-02037-5

  • Nerius M, Doblhammer G, Tamgüney G
    GI infections are associated with an increased risk of Parkinson’s disease
    Gut 66, 1-2 (2020)
    https://doi.org/10.1136/gutjnl-2019-318822

  • Wüsten KA, Reddy PP, Smiyakin A, Bernis ME, Tamgüney G
    A bioluminescent cell assay to quantify prion protein dimerization
    Sci Rep 8, 14178 (2018)
    https://doi.org/10.1038/s41598-018-32581-1

  • Tamgüney G and Korczyn AD
    A critical review of the prion hypothesis of human synucleinopathies
    Cell Tissue Res 373, 213-220 (2017)
    https://doi.org/10.1007/s00441-017-2712-y

  • Breid S, Bernis ME, Babila JT, Garza MC, Wille H, Tamgüney G
    Bioluminescence imaging of neuroinflammation in transgenic mice after peripheral inoculation of alpha-synuclein fibrils
    J Vis Exp (122) e55503 (2017)
    https://doi.org/10.3791/55503

  • Tachu BJ, Wüsten KA, Garza MC, Wille H, Tamgüney G
    An easy method for bacterial expression and purification of wild-type and mutant superoxide dismutase 1 (SOD1)
    Protein Expr Purif 134, 63-71 (2017)
    https://doi.org/10.1016/j.pep.2017.04.001

  • Breid S, Bernis ME, Babila JT, Garca MC, Wille H, Tamgüney G
    Neuroinvasion of α-synuclein prionoids after intraperitoneal and intraglossal inoculation
    J Virol 90, 9182-9193 (2016)
    https://doi.org/10.1128/JVI.01399-16

  • Bernis ME, Babila JT, Breid S, Wüsten KA, Wüllner U, Tamgüney G
    Prion-like propagation of human brain-derived alpha-synuclein in transgenic mice expressing human wild-type alpha-synuclein
    Acta Neuropathol Commun 3, 75 (2015)
    https://doi.org/10.1186/s40478-015-0254-7

  • Tamgüney G, Giles K, Oehler A, Johnson NL, DeArmond SJ, Prusiner SB
    Chimeric elk/mouse prion proteins in transgenic mice
    J Gen Virol 94, 443-452 (2013)
    https://doi.org/10.1099/vir.0.045989-0

  • Tamgüney G, Richt JA, Hamir AN, Greenlee JJ, Miller MW, Wolfe LL, Sirochman TM, Young AJ, Glidden DV, Johnson NL, Giles K, DeArmond SJ, Prusiner SB
    Salivary prions in sheep and deer
    Prion 6, 52-61(2012)
    https://doi.org/10.4161/pri.6.1.16984

  • Tamgüney G, Miller WM, Wolfe LL, Sirochman TM, Glidden DV, Palmer C, Lemus A, DeArmond SJ, Prusiner SB
    Asymptomatic deer excrete infectious prions in feces
    Nature 461, 529-532 (2009)
    https://doi.org/10.1038/nature08289

  • Tamgüney G, Francis KP, Giles K, Lemus A, DeArmond SJ, Prusiner SB
    Measuring prions by bioluminescence imaging
    Proc Natl Acad Sci U S A 106, 15002-15006 (2009)
    https://doi.org/10.1073/pnas.0907339106

  • Tamgüney G, Miller WM, Giles K, Lemus A, Glidden DV, DeArmond SJ, Prusiner SB
    Transmission of scrapie and sheep-passaged bovine spongiform encephalopathy prions to transgenic mice expressing elk prion protein
    J Gen Virol 90, 1035-1047 (2009)
    https://doi.org/10.1099/vir.0.007500-0

  • Tamgüney G, Giles K, Glidden DV, Lessard P, Wille H, Tremblay P, Groth DF, Yehiely F, Korth C, Moore RC, Tatzelt J, Rubinstein E, Boucheix C, Yang X, Stanley P, Lisanti MP, Dwek RA, Rudd PM, Moskovitz J, Epstein CJ, Dawson Cruz T, Kuziel WA, Maeda N, Sap J, Hsiao Ashe K, Carlson GA, Tesseur I, Wyss-Coray T, Mucke L, Weisgraber KH, Mahley RW, Cohen FE, Prusiner SB
    Genes contributing to prion pathogenesis
    J Gen Virol 89, 1777-1788 (2008)
    https://doi.org/10.1099/vir.0.2008/001255-0

  • Safar JG, Lessard P, Tamgüney G, Freyman Y, Deering C, Letessier F, DeArmond SJ, Prusiner SB
    Transmission and detection of prions in feces
    J Infect Dis 198, 81-89 (2008)
    https://doi.org/10.1086/588193

  • Tamgüney G, Giles K, Bouzamondo-Bernstein E, Bosque PJ, Miller MW, Safar J, DeArmond SJ, Prusiner SB
    Transmission of elk and deer prions to transgenic mice
    J Virol 80, 9104-9114 (2006)
    https://doi.org/10.1128/JVI.00098-06

  • Tamgüney G, van Snick J, Fickenscher H
    Autocrine stimulation of rhadinovirus-transformed T cells by the chemokine CCL1/I-309 Oncogene 23, 8475-8485 (2004)
    https://doi.org/10.1038/sj.onc.1207903

  • Greve T*, Tamgüney G*, Fleischer B, Fickenscher H, Bröker BM
    Downregulation of p56lck kinase activity in T cells of squirrel monkeys (Saimiri sciureus) correlates with the non-transforming and apathogenic properties of herpesvirus saimiri in its natural host
    J Virol 75, 9252-9261 (2001) (*equal contribution)
    https://doi.org/10.1210/jcem.86.11.7998

  • Gröschl M, Rauh M, Wagner R, Neuhuber W, Metzler M, Tamgüney G, Zenk J, Schoof E, Dörr HG, Blum WF, Rascher W, Dötsch J
    Identification of leptin in human saliva
    J Clin Endocrinol Metab 86, 5234-5239 (2001)
    https://doi.org/10.1210/jcem.86.11.7998

  • Hiller C, Tamgüney G, Stolte N, Mätz‑Rensing K, Lorenzen D, Hör S, Thurau M, Wittmann S, Slavin S, Fickenscher H
    Herpesvirus saimiri pathogenicity enhanced by thymidine kinase of herpes simplex virus
    Virology 278, 445‑455 (2000)
    https://doi.org/10.1006/viro.2000.0665