Pils M, Dybala A, Schaffrath S, Rehn F, Kutzsche J, Blömeke L, Tusche M, Özdüzenciler P, Bujnicki T, Kraemer-Schulien V, Gramespacher H, Schmieschek MHT, Barbe MT, Onur ÖA, Fink GR, Tamgüney G, Bannach O, Willbold D Elevated Aβ aggregates in feces from Alzheimer’s disease patients: a proof-of-concept study Alzheimer's Research & Therapy, accepted (2024) https://doi.org/10.
Schulz CM, Agerschou ED, Gardon L, Alexander M, Stoldt M, Heise H, Tamgüney G, Hoyer W Disordered regions of inhibitor-bound α-synuclein suppress seed-induced fibril nucleation in cells Cell Reports Physical Science, pre-accepted (2024) https://doi.org/10.
Weber TM, Özdüzenciler P, Tamgüney G, Pietruszka J Utilization of a Branched Late-Stage Clickable Biotinylated Chassis on the Example of a Pittsburgh B Analog Organic Letters, 26, 6771-6775 (2024) https://doi.org/10.1021/acs.orglett.4c02527
Holtz AV, Fink A, Tamgüney G, Doblhammer G Colonoscopy and subsequent risk of Parkinson’s disease J Parkinsons Dis, 14, 747-760 (2024) https://doi.org/10.3233/JPD-240017
Flores-Fernandez JM, Pesch V, Sriraman A, Chimal Juarez E, Amidian S, Wang X, Duckering C, Fang A, Reithofer S, Ma L, Cortez LM, Sim VL, Tamgüney G, Wille H Rational design of structure-based vaccines targeting misfolded alpha-synuclein conformers of Parkinson’s disease and related disorders Bioeng Transl Med, 9, e10665 (2024) https://doi.org/10.1002/btm2.10665
Reineke B, Paulus I, Löffelsend S, Yu CH, Vinogradov D, Meyer A, Hazur J, Röder J, Vollmer M, Tamgüney G, Hauschild S, Boccaccini AR, Groll J, Förster S On-chip fabrication and in-flow 3D-printing of microgel constructs: from chip to scaffold materials in one integral process Biofabrication, 16 (2024) https://doi.org/10.1088/1758-5090/ad3318
Pesch V, Flores-Fernandez JM, Reithofer S, Ma L , Özdüzenciler P, Busch Y, Sriraman A, Wang YL, Amidian S, Kroepel CVM, Müller L, Lien Y, Rudtke O, Frieg B, Schröder GF, Wille H, Tamgüney G Vaccination with structurally adapted fungal protein fibrils induces immunity to Parkinson's disease Brain, 147, 1644-1652 (2024) https://doi.org/10.1093/brain/awae061
Kuzkina A, Rößle J, Seger A, Panzer C, Kohl A, Maltese V, Musacchio T, Blaschke S, Tamgüney G, Kaulitz S, Rak K, Scherzad A, Zimmermann P, Klussmann J, Hackenberg S, Volkmann J, Sommer C, Sommerauer M, Doppler K Combining skin and olfactory α-synuclein seed amplification assays (SAA) - towards biomarker-driven phenotyping in synucleinopathies NPJ Parkinsons Dis, 9, 14 (2023) https://doi.org/10.1038/s41531-023-00519-8
Rakuša E, Fink A, Tamgüney G, Heneka MT, Doblhammer G Sporadic Use of Antibiotics in Older Adults and the Risk of Dementia: A Nested Case–Control Study Based on German Health Claims Data J Alzheimers Dis, 93, 1329-1339 (2023) https://doi.org/10.3233/JAD-221153
Altendorf T, Gering I, Santiago-Schübel B, Aghabashlou Saisan S, Tamgüney G, Tusche M, Honold D, Schemmert S, Hoyer W, Mohrlüder J, Willbold D Stabilization of Monomeric Tau Protein by All D-Enantiomeric Peptide Ligands as Therapeutic Strategy for Alzheimer's Disease and Other Tauopathies Int J Mol Sci, 24, 2161 (2023) https://doi.org/10.3390/ijms24032161
Schaffrath A, Schleyken S, Seger A, Jergas H, Özdüzenciler P, Pils M, Blömeke L, Cousin A, Willbold J, Bujnicki T, Bannach O, Fink GR, Willbold D, Sommerauer M, Barbe MT, Tamgüney G Patients with isolated REM-sleep behavior disorder have elevated levels of alpha-synuclein aggregates in stool NPJ Parkinsons Dis, 9, 14 (2023) https://doi.org/10.1038/s41531-023-00458-4
Blömeke L, Pils M, Kraemer-Schulien V, Dybala A, Schaffrath A, Kulawik A, Zack R, Tropea TF, Bujnicki T, Tamgüney G, Weintraub D, Irwin D, Grossman M, Wolk DA, Trojanowski JQ, Bannach O, Chen-Plotkin A, Rehn F, Cousin A, Nischwitz V, Willbold J, Willbold D Quantitative detection of α-synuclein and tau oligomers and other aggregates by digital single particle counting NPJ Parkinsons Dis, 8, 68 (2022) https://doi.org/10.1038/s41531-022-00330-x
Lohmann S, Grigoletto J, Bernis ME, Pesch V, Ma L, Reithofer S, Tamgüney G Ischemic stroke causes Parkinson's disease-like pathology and symptoms in transgenic mice overexpressing alpha-synuclein Acta Neuropathol Commun, 10, 26 (2022) https://rdcu.be/cHITe
Woerman AL and Tamgüney G Body-first Parkinson’s disease and variant Creutzfeldt–Jakob disease – similar or different? Neurobiol Dis, 164, 105625 (2022) https://doi.org/10.1016/j.nbd.2022.105625
Fink A, Doblhammer G, Tamgüney G Recurring gastrointestinal infections increase the risk of dementia J Alzheimers Dis 84, 797-806 (2021) https://doi.org/10.3233/JAD-210316
Santur K, Reinartz E, Lien Y, Tusche M, Altendorf T, Sevenich M, Tamgüney G, Mohrlüder J, Willbold D Ligand-induced stabilization of the native human superoxide dismutase 1 ACS Chem Neurosci 12, 2520-2528 (2021) https://doi.org/10.1021/acschemneuro.1c00253
Van Den Berge N, Ferreira N, Mikkelsen TW, Alstrup AKO, Tamgüney G, Karlsson P, Terkelsen AJ, Nyengaard JR, Jensen PH, Borghammer P Ageing promotes pathological alpha-synuclein propagation and autonomic dysfunction in wild-type rats Brain 144, 1853-1868 (2021) https://doi.org/10.1093/brain/awab061
Bernis ME and Tamgüney G Bioluminescence imaging of neuroinflammation in a mouse model of Parkinson's disease Methods Mol Biol 2081, 147-159 (2020) https://doi.org/10.1007/978-1-4939-9940-8_10
Van Den Berge N, Ferreira N, Gram H, Mikkelsen TW, Alstrup AKO, Casadei N, Tsung-Pin P, Riess O, Nyengaard JR, Tamgüney G, Jensen PH, Borghammer P Evidence for bidirectional and trans-synaptic parasympathetic and sympathetic propagation of alpha-synuclein in rats Acta Neuropathol 138, 535-550 (2019) https://doi.org/10.1007/s00401-019-02040-w
Lohmann S, Bernis ME, Babila JT, Ziemski A, Grigoletto J, Tamgüney G Oral and intravenous transmission of α-synuclein fibrils to mice Acta Neuropathol 138, 515-533 (2019) https://doi.org/10.1007/s00401-019-02037-5
Nerius M, Doblhammer G, Tamgüney G GI infections are associated with an increased risk of Parkinson’s disease Gut 66, 1-2 (2020) https://doi.org/10.1136/gutjnl-2019-318822
Wüsten KA, Reddy PP, Smiyakin A, Bernis ME, Tamgüney G A bioluminescent cell assay to quantify prion protein dimerization Sci Rep 8, 14178 (2018) https://doi.org/10.1038/s41598-018-32581-1
Tamgüney G and Korczyn AD A critical review of the prion hypothesis of human synucleinopathies Cell Tissue Res 373, 213-220 (2017) https://doi.org/10.1007/s00441-017-2712-y
Breid S, Bernis ME, Babila JT, Garza MC, Wille H, Tamgüney G Bioluminescence imaging of neuroinflammation in transgenic mice after peripheral inoculation of alpha-synuclein fibrils J Vis Exp (122) e55503 (2017) https://doi.org/10.3791/55503
Tachu BJ, Wüsten KA, Garza MC, Wille H, Tamgüney G An easy method for bacterial expression and purification of wild-type and mutant superoxide dismutase 1 (SOD1) Protein Expr Purif 134, 63-71 (2017) https://doi.org/10.1016/j.pep.2017.04.001
Breid S, Bernis ME, Babila JT, Garca MC, Wille H, Tamgüney G Neuroinvasion of α-synuclein prionoids after intraperitoneal and intraglossal inoculation J Virol 90, 9182-9193 (2016) https://doi.org/10.1128/JVI.01399-16
Bernis ME, Babila JT, Breid S, Wüsten KA, Wüllner U, Tamgüney G Prion-like propagation of human brain-derived alpha-synuclein in transgenic mice expressing human wild-type alpha-synuclein Acta Neuropathol Commun 3, 75 (2015) https://doi.org/10.1186/s40478-015-0254-7
Tamgüney G, Giles K, Oehler A, Johnson NL, DeArmond SJ, Prusiner SB Chimeric elk/mouse prion proteins in transgenic mice J Gen Virol 94, 443-452 (2013) https://doi.org/10.1099/vir.0.045989-0
Tamgüney G, Richt JA, Hamir AN, Greenlee JJ, Miller MW, Wolfe LL, Sirochman TM, Young AJ, Glidden DV, Johnson NL, Giles K, DeArmond SJ, Prusiner SB Salivary prions in sheep and deer Prion 6, 52-61(2012) https://doi.org/10.4161/pri.6.1.16984
Tamgüney G, Miller WM, Wolfe LL, Sirochman TM, Glidden DV, Palmer C, Lemus A, DeArmond SJ, Prusiner SB Asymptomatic deer excrete infectious prions in feces Nature 461, 529-532 (2009) https://doi.org/10.1038/nature08289
Tamgüney G, Francis KP, Giles K, Lemus A, DeArmond SJ, Prusiner SB Measuring prions by bioluminescence imaging Proc Natl Acad Sci U S A 106, 15002-15006 (2009) https://doi.org/10.1073/pnas.0907339106
Tamgüney G, Miller WM, Giles K, Lemus A, Glidden DV, DeArmond SJ, Prusiner SB Transmission of scrapie and sheep-passaged bovine spongiform encephalopathy prions to transgenic mice expressing elk prion protein J Gen Virol 90, 1035-1047 (2009) https://doi.org/10.1099/vir.0.007500-0
Tamgüney G, Giles K, Glidden DV, Lessard P, Wille H, Tremblay P, Groth DF, Yehiely F, Korth C, Moore RC, Tatzelt J, Rubinstein E, Boucheix C, Yang X, Stanley P, Lisanti MP, Dwek RA, Rudd PM, Moskovitz J, Epstein CJ, Dawson Cruz T, Kuziel WA, Maeda N, Sap J, Hsiao Ashe K, Carlson GA, Tesseur I, Wyss-Coray T, Mucke L, Weisgraber KH, Mahley RW, Cohen FE, Prusiner SB Genes contributing to prion pathogenesis J Gen Virol 89, 1777-1788 (2008) https://doi.org/10.1099/vir.0.2008/001255-0
Safar JG, Lessard P, Tamgüney G, Freyman Y, Deering C, Letessier F, DeArmond SJ, Prusiner SB Transmission and detection of prions in feces J Infect Dis 198, 81-89 (2008) https://doi.org/10.1086/588193
Tamgüney G, Giles K, Bouzamondo-Bernstein E, Bosque PJ, Miller MW, Safar J, DeArmond SJ, Prusiner SB Transmission of elk and deer prions to transgenic mice J Virol 80, 9104-9114 (2006) https://doi.org/10.1128/JVI.00098-06
Tamgüney G, van Snick J, Fickenscher H Autocrine stimulation of rhadinovirus-transformed T cells by the chemokine CCL1/I-309 Oncogene 23, 8475-8485 (2004) https://doi.org/10.1038/sj.onc.1207903
Greve T*, Tamgüney G*, Fleischer B, Fickenscher H, Bröker BM Downregulation of p56lck kinase activity in T cells of squirrel monkeys (Saimiri sciureus) correlates with the non-transforming and apathogenic properties of herpesvirus saimiri in its natural host J Virol 75, 9252-9261 (2001) (*equal contribution) https://doi.org/10.1210/jcem.86.11.7998
Gröschl M, Rauh M, Wagner R, Neuhuber W, Metzler M, Tamgüney G, Zenk J, Schoof E, Dörr HG, Blum WF, Rascher W, Dötsch J Identification of leptin in human saliva J Clin Endocrinol Metab 86, 5234-5239 (2001) https://doi.org/10.1210/jcem.86.11.7998
Hiller C, Tamgüney G, Stolte N, Mätz‑Rensing K, Lorenzen D, Hör S, Thurau M, Wittmann S, Slavin S, Fickenscher H Herpesvirus saimiri pathogenicity enhanced by thymidine kinase of herpes simplex virus Virology 278, 445‑455 (2000) https://doi.org/10.1006/viro.2000.0665
